Publication date: May 31, 2021
Hyperpolarization by dissolution dynamic nuclear polarization (dDNP) has enabled promising applications in spectroscopy and imaging, but remains poorly widespread due to experimental complexity. Broad democratization of dDNP would require remote preparation and distribution of hyperpolarized samples from dedicated facilities. We describe here new hyperpolarizing polymers (HYPOPs) that can generate radical- and contaminant-free hyperpolarized samples within minutes with lifetimes exceeding hours in the solid state. HYPOPs feature tunable macroporous porosity, with porous volumes up to 80% and concentration of nitroxide radicals grafted in the bulk matrix up to 285 μmol g-1. Analytes can be efficiently impregnated as aqueous/alcoholic solutions and hyperpolarized up to P(13C) =25% within 8 min, through the combination of 1H spin diffusion and 1H →13C cross polarization. Solutions of 13C-analytes of biological interest hyperpolarized in HYPOPs display a very long solid-state 13C relaxation times of 5.7 h at 3.8 K, thus prefiguring transportation over long distances.
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BET data.zip
MD5md5:e8c4a6a7a71cbb6a91e1f0810b7b5303
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158.5 KiB | N2 adsorption isotherms of porous polymers containing XX mmol/g of nitroxide radicals. |
Dissolution data.zip
MD5md5:55adc12a696abc173e16eb7c95bb03cc
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25.2 MiB | Raw NMR files (Topspin format) related to dissolution experiments |
DNP data.zip
MD5md5:a88f9f4b5dda410050cea6a4403193ec
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255.5 MiB | Raw NMR files (Topspin format) related to DNP experiments |
Poro Hg.zip
MD5md5:0731c10ab6faed04949b046a842e9b37
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63.3 KiB | Hg intrusion porosimetry of porous polymers containing XX mmol/g of nitroxide radicals. |
RPE data.zip
MD5md5:9ae778c99acd97350ddb7109b7850f31
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369.2 KiB | RPE characterization of porous polymers |
Scripts_Matlab.zip
MD5md5:0fc9a5426aab8ef354175ed648c2a80b
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16.1 KiB | Matlab scripts for generating the graphs shown in the paper |
2021.79 (version v1) [This version] | May 31, 2021 | DOI10.24435/materialscloud:kv-6q |